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Fallen US biotech star Elizabeth Holmes must begin serving prison time after a judge denied her latest request to remain free while appealing her fraud conviction.

More than 100 soldiers with sniffer dogs were searching for four missing indigenous children who were traveling in an airplane that crashed in the Colombian Amazon two weeks ago, killing three adults, the armed forces said on Wednesday.

Brentford striker Ivan Toney promised to return to "playing the game I love" after being banned from all football-related activity for eight months over breaches of betting rules.

Like humans, baboons get by with a little help from their friends.

A Hebrew Bible more than 1,000 years old sold for $38.1 million in New York on Wednesday, setting a record for the most valuable manuscript ever sold at auction.

The premiere of Spanish director Pedro Almodovar's queer Western, with Ethan Hawke and Pedro Pascal as tormented lovers, received rave reviews at the Cannes Film Festival on Wednesday and left many wanting more.

Dustin Johnson says LIV Golf stars have nothing to prove at this week's PGA Championship and that was true before three players finished in the top six at the Masters.

Japan's Palme d'Or winner Hirokazu Kore-eda unveiled his new movie "Monster" at Cannes on Wednesday, a heartwarming tale despite its ominous title.

At least nine people died in Italy's northern Emilia Romagna region as heavy rains flooded rivers and submerged entire neighbourhoods and farmland Wednesday, prompting the cancellation of this weekend's Imola Grand Prix.

A British director, two noted Brazilian Indigenous activists, and 13 others were ambushed by dozens of armed men accused of illegally occupying territory in an Indigenous reservation in the Brazilian Amazon, people involved said Wednesday.

Syrian President Bashar al-Assad will attend this week his first Arab League summit in 13 years, his foreign minister said Wednesday, signalling regional reintegration after more than a decade of war.

Roma manager Jose Mourinho said on Wednesday he has adopted a more selfless attitude in recent years.

United States Ryder Cup captain Zach Johnson said players from the LIV Golf League are "not on my radar" but would not shut down contact from anyone interested in facing Europe.

Delhi Capitals survived a blazing 94 by Liam Livingstone for a consolation 15-run win on Wednesday to push Punjab Kings to the brink of IPL elimination on Wednesday.

Tariq Ramadan's lawyers pleaded Wednesday for the controversial Islamic scholar to be acquitted on the third and final day of his trial in Geneva on charges of rape and sexual coercion.

A high-tech Patriot air defense system provided to Ukraine suffered damage but is still working, a US defense official said Wednesday.

Reigning US Open champion Matthew Fitzpatrick said the crucial lessons he learned contending for a title at last year's PGA Championship helped him win his first major a month later.

On a sandy lot below a Khartoum apartment building, helmetless Sudanese soldiers in a mishmash of uniforms raised their fists as machine gunners blasted away from atop two small trucks.

Publisher Penguin Random House and the writers' group PEN America filed a lawsuit on Wednesday against a Florida school district over the removal of books from public school libraries that address race and LGBTQ issues.

Rafael Nadal will announce if he will compete in the French Open on Thursday, amid a long-term injury struggle and some Spanish reports that he will withdraw.

Eder Militao returned to the heart of the Real Madrid defence for Wednesday's Champions League semi-final, second leg against Manchester City in the only change in either side from the first leg, which ended 1-1.

Ukraine's foreign minister met China's special envoy to Kyiv on Wednesday, insisting that the war-torn country would not accept a peace plan that relied on giving up territory after Russia's invasion.

James Milner will leave Liverpool when his contract expires at the end of the season, the Premier League giants announced Wednesday as they confirmed several departures from Anfield.

Brentford striker Ivan Toney has been banned from all football-related activity for eight months over breaches of betting rules.

Prince Harry and wife Meghan Markle were involved in a "near catastrophic car chase" involving paparazzi in New York, a spokesperson for the couple said Wednesday.

The dollar rose while stocks moved in different directions on Wednesday as investors track talks aimed at breaking an impasse over raising the US debt ceiling.

Johnny Depp dismissed years of negative press over his tumultuous marriage to Amber Heard, telling the Cannes Film Festival on Wednesday that most of the stories about him were "fantastically, horrifically written fiction".

French judo legend Teddy Riner, fresh from being crowned world champion, can breathe a sigh of relief after The International Judo Federation (IJF) admitted Wednesday it should have been his opponent Inal Tasoev who took gold.

President Joe Biden said Wednesday he is confident a deal can be reached with Republicans leaders to avert a potentially catastrophic US debt default as early as June 1.

At least eight people died in Italy's northern Emilia Romagna region as heavy rains flooded rivers and submerged entire neighbourhoods and farmland Wednesday, prompting the cancellation of this weekend's Imola Grand Prix.

In his darkest moments battling back pain and vertigo, Jason Day had already written the epitaph on his career, so winning last week was a joyful reward for fighting through.

US lawmakers on a new committee pressing a tough line on China will seek cooperation with Britain on their first foreign visit, people involved said Wednesday.